- [n] DEDGRL - Substance Search
- [n] Wikipedia
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions.
SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the presynaptic cell.[2] They have varying degrees of selectivity for the other monoamine transporters, with pure SSRIs having strong affinity for the serotonin transporter and only weak affinity for the norepinephrine and dopamine transporters.
SSRIs are the most widely prescribed antidepressants in many countries.[3] The efficacy of SSRIs in mild or moderate cases of depression has been disputed[4] and may or may not be outweighed by side effects, especially in adolescent populations.[5][6][7][8]
Selective Serotonin Reuptake Inhibitor or SSRIs are a class of antidepressants which include the following drugs;
- Citalopram: Also known by the brand name Celexa.
- Escitalopram: Also known by the brand name Lexapro.
- Fluoxetine: Also known by the brand names Prozac, Sarafem, and Symbyax.
- Fluvoxamine: Also known by the brand names Luvox and Luvox CR.
- Paroxetine: Also known by the brand names Paxil and Pexeva.
- Sertraline: Also known by the brand name Zoloft.
- Vilazodone: Also known by the brand name Viibryd.